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Treatment of Recurrent or Progressive Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)

For information about the treatments listed below, see the Treatment Option Overview section.

Treatment of pancreatic neuroendocrine tumors (NETs) that continue to grow during treatment or recur (come back) may include the following:

  • Surgery to remove the tumor.
  • Chemotherapy.
  • Hormone therapy.
  • Targeted therapy.
  • For liver metastases:
    • Regional chemotherapy.
    • Hepatic arterial occlusion or chemoembolization, with or without systemic chemotherapy.
  • A clinical trial of a new therapy.

To Learn More About Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)

For more information from the National Cancer Institute about pancreatic neuroendocrine tumors (NETs), see the following:

For general cancer information and other resources from the National Cancer Institute, visit:

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

This information is not intended to replace the advice of a doctor. Navigating Care disclaims any liability for the decisions you make based on this information. This information was sourced and adapted from Adapted from the National Cancer Institute's Physician Data Query (PDQ®) Cancer Information Summaries on www.cancer.gov.

See Expert Resources

The Navigating Care Library includes articles about cancer, chemotherapy regimens and drugs from the the National Cancer Institute and other experts.